I am Dominic Franck, HPLC expert und trainer.
I help HPLC users and laboratories develop methods reliably, conduct scientifically sound validations, and systematically resolve HPLC issues.
My particular area of focus is radio-HPLC.
My areas of HPLC expertise
Radio-HPLC
Fundamentals, validation, radio-detectors, and practical application of radio-HPLC methods.
Method Development
Develop systematically HPLC methods and gear them towards robust application.
HPLC Validation
Validation strategies, experimental design, acceptance criteria, and documentation from a technical perspective.
Troubleshooting
Systematically narrow down the causes of baseline drift, peak tailing, poor precision, and other method-related issues.
Practical HPLC Knowledge
I am Dominic Franck. My areas of expertise include HPLC method development, method validation, troubleshooting, and radio-HPLC.
I am familiar with the challenges of daily laboratory work and support HPLC users and lab teams in gaining a better understanding of methods, analyzing problems systematically, and building technical confidence.
25 years of HPLC experience
15 years of Radio-HPLC specialist
From Laboratory Technician to Department Manager
Proven process for method development
The HPLC Academy for your daily laboratory practice
The HPLC Academy complements your personal support with structured HPLC expertise, courses, practical videos, templates, and a knowledge-based HPLC agent.
- HPLC knowledge base
- Radio-HPLC knowledge
Courses and learning content
- Many practical videos
- Checklists and templates
- Content on validation and troubleshooting
- Knowledge-based HPLC agent
Start immediately
Get free access and download the validation checklist right away. Watch the video series “The 7 Most Fatal Validation Mistakes” and achieve your first quick wins in the lab—risk-free and with no obligation.
Lay the foundation
Start with the basic HPLC validation course (online, self-paced) and master the fundamentals at your own pace.
Enable team
Scale knowledge with tailored workshops for your entire team, on-site or online.
Staying excellent
Secure long-term expertise through individual mentoring – for complex HPLC challenges.
The Validation Starter Kit
Achieve immediate improvements for your laboratory.
Get login access to the HPLC Academy knowledge base and receive the starter kit, featuring the “Smart Validation” checklist, the “7 Fatal Validation Errors” video series, the HPLC basics guide, and the ultimate HPLC troubleshooting guide. Everything is free and ready for immediate use in your laboratory.
No Spam, it’s a promised!
Immediate download
No credit card required
More than training:
Technical support in day-to-day laboratory work
Knowledge is especially helpful when it is available at the right moment. With the HPLC Academy, the knowledge-based HPLC agent, and my personal support, you will find structured next steps — even for complex HPLC questions.
Technical support for HPLC-related questions
Baseline drift, peak tailing, or validation issues?
Is your validated method suddenly failing and showing double peaks?
I’ll provide immediate support for your HPLC challenge, review your chromatograms with you, and help identify the possible causes.
Together, we’ll determine the next logical steps.
Radio-HPLC: Technical support for your application
Radio-HPLC places specific demands on the method, system, detection, and validation.
I can assist you with specific challenges, the development and validation of radio-chromatographic methods, and the selection of a suitable HPLC system and radio-detector.
Together, we will evaluate your requirements and find a solution that suits your application and your laboratory.
Frequently Asked Questions (FAQ)
Is the support also suitable for our specific method and our laboratory?
> Yes. I work with your laboratory’s actual research questions, methods, and data. In doing so, I take into account factors such as the type of instrument used, the method, the matrix, the detection system, and your requirements regarding development, validation, or routine operation.
With which HPLC problems can you provide assistance?
> The issues encountered in HPLC and radio-HPLC are highly varied. I provide support in areas such as method development, validation, and troubleshooting, addressing problems like baseline drift, peak tailing, poor precision, low recovery, retention time shifts, carry-over, unexpected peaks, and other method performance issues.
Do you also provide support for specific radio-HPLC projects?
> Yes. I can assist you with issues regarding radio-HPLC methods, method development and validation, as well as the selection and optimization of a suitable HPLC system and radio-detector.
Together, we will assess your requirements and devise an appropriate approach for your application.
Do you also provide support with method development and validation?
> Yes. I provide support with the planning, measurement, and evaluation of method development and validation, as well as with the selection of suitable parameters, acceptance criteria, data analysis, and documentation. Since validation processes may involve confidential data, I work under a non-disclosure agreement (NDA).
Who is your offer suitable for?
For HPLC users, lab managers, QC personnel, and analytical teams from the (radio)pharmaceutical, biotech, CDMO, and CRO sectors, as well as related fields. This support is suitable for both beginners and experienced users.
How soon can we start?
The first step is a brief initial consultation (schedule an initial consultation) to discuss your specific issue and the available information. We then determine whether troubleshooting, a review of methods or validation, training, or long-term support would be appropriate.
My Values
Scientific excellence – only validated, evidence-based knowledge
Practical applicability – everything must work in the laboratory.
Empowerment – I turn people into experts, not dependents.
How can I support you?
Whether it’s radio-HPLC, method development, validation, or troubleshooting — briefly describe your issue to me. Together, we’ll determine the best next step.